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Moumoujus

ANGELICA ACUTILOBA ROOT.

Valuable CAS 164288-49-7 / SKIN CONDITIONING

Angelica Acutiloba Root is a potent botanical extract recognized for its remarkable anti-aging and brightening capabilities. It effectively enhances skin elasticity and diminishes hyperpigmentation, promoting a visibly more even and youthful complexion.

Summary

Skin conditioning Soothing Antioxidant Anti-aging Brightening Anti-inflammatory

Science

Mechanism of Action

This extract primarily acts by inhibiting matrix metalloproteinases (MMPs) while increasing tissue inhibitors of metalloproteinases (TIMP-1), thus protecting collagen. It also brightens skin by promoting lysosomal enzyme activity that degrades melanosome complexes, alongside providing antioxidant and anti-inflammatory benefits.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

2%

Key findings

  1. 01 Park et al., Toxicology Research (2017) 33(2):125–134
  2. 02 Maruzen Pharmaceuticals (Internal Clinical Data/Product Technical Bulletin)

Transparency

Dusting Analysis

Not commonly dusted

There is no available data suggesting that Angelica Acutiloba Root is commonly dusted in cosmetic formulations.

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 7.5
0 7 14

Stability

Highly stable in aqueous solutions, often supplied in Butylene Glycol. It remains stable under standard storage conditions but can be sensitive to extreme oxidation due to its polyphenol content.

Conflicts

  • Strong oxidizing agents
  • Highly alkaline environments (may degrade sensitive phytoconstituents like ferulic acid)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

While not yet formally reviewed by the CIR, this ingredient is widely used in J-Beauty and K-Beauty products. The presence of furocoumarins in the plant could theoretically cause photosensitivity if highly concentrated in the final extract.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

This multi-functional ingredient offers significant benefits for anti-aging and brightening, supported by promising preclinical and clinical data, making it a strong asset for diverse skincare formulations.

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