Science
Mechanism of Action
It enhances skin brightness by accelerating melanosome degradation within keratinocytes via lysosomal enzyme activation. Concurrently, it offers anti-aging benefits by inhibiting MMPs, stimulating collagen synthesis, and providing antioxidant protection.
Research
Clinical Evidence
High confidence2%
Key findings
- 01 Clinical application of a 2% cream significantly improved age spots and hyperpigmentation.
- 02 In vitro studies demonstrated a 36.6% reduction in MMP-2 activity and stimulated collagen synthesis, suggesting anti-photoaging potential.
Transparency
Dusting Analysis
With proven efficacy at a 2% concentration, this extract is typically formulated at active levels and not commonly associated with dusting practices.
The Formula
Formulation
Stability
Highly stable in aqueous solutions, it is easily incorporated into water-based serums or the water phase of emulsions. Excellent stability is reported in commercial BG-extracted formats.
Conflicts
- Strong oxidizing agents
- Highly alkaline environments (may degrade phenolic components)
Safety
Safety Profile
While not formally reviewed by the CIR for the leaf, oral toxicity studies suggest low systemic toxicity. It contains furanocoumarins, which are known photosensitizers and may cause dermatitis at high concentrations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Angelica Acutiloba Leaf Extract is a valuable ingredient for targeting hyperpigmentation and signs of aging across all skin types, with careful consideration for its photosensitizing potential.
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References
Sources