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Moumoujus

ANGELICA ACUTILOBA FLOWER EXTRACT.

Valuable CAS - / SKIN CONDITIONING

This potent botanical extract offers multifaceted benefits, targeting signs of aging, hyperpigmentation, and overall skin health. It works to rejuvenate skin by protecting collagen and improving elasticity.

Summary

skin conditioning antioxidant soothing anti-aging brightening

Science

Mechanism of Action

It inhibits Matrix Metalloproteinases (MMPs) to prevent collagen breakdown and stimulates Type I procollagen synthesis. Additionally, it suppresses melanin production by reducing tyrosinase activity and exhibits senolytic activity to eliminate 'zombie' cells.

Research

Clinical Evidence

High confidence
Effective range 0.01–1%
Optimal

1%

Key findings

  1. 01 Anti-Photoaging Effects of Angelica acutiloba Root Ethanol Extract in Human Dermal Fibroblasts, NIH PMC (2015)
  2. 02 Advanced Biology / Keio University School of Medicine (2024)
  3. 03 Journal of Cosmetic Dermatology / MDPI (2023)

Transparency

Dusting Analysis

Not commonly dusted

No specific data on dusting available. Plant extracts are generally less prone to dusting than potent pure actives.

The Formula

Formulation

Solubility
Both
Optimal pH 5 – 7.5
0 7 14

Stability

Ethanolic and glycolic extracts are common. Active phthalides are light-sensitive and prone to oxidation, requiring airtight, opaque packaging. Stability is optimal in slightly acidic to neutral pH environments.

Conflicts

  • Strong oxidizing agents
  • High heat during processing (may degrade volatile phthalides)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While not formally reviewed by CIR, it is classified as a 'Skin Conditioning' agent in EU CosIng. Genotoxicity tests for the genus are negative, and it has a long history of safe use in Kampo medicine.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Angelica Acutiloba Flower Extract is a valuable ingredient for comprehensive skin rejuvenation, targeting aging, hyperpigmentation, and overall skin vitality with a strong scientific basis.

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