Science
Mechanism of Action
This extract stimulates adipocyte differentiation and lipid accumulation, delivering a 'lipofilling' effect for increased volume. Additionally, it inhibits tyrosinase activity to reduce melanin and suppresses MMP-1 to minimize wrinkle formation.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 NIH (PubMed 31215053) found 0.25% timosaponin A-III significantly reduced facial wrinkles over 12 weeks.
- 02 Sederma's internal study showed 5% Volufiline (AARE in Hydrogenated Polyisobutene) increased breast volume by 2.2% in 56 days.
- 03 MDPI Cosmetics (2023) validated 2% AARE as a natural skin-whitening agent.
Transparency
Dusting Analysis
There is no specific data indicating this ingredient is commonly 'dusted' or used in sub-efficacious concentrations within formulations.
The Formula
Formulation
Stability
Stable in both O/W and W/O emulsions, remaining effective up to 80°C; its primary active is lipid-soluble, while some components are water-soluble.
Conflicts
- Strong oxidizing agents
- Highly acidic environments (pH < 4.0 may degrade saponins)
Safety
Safety Profile
Despite limited CIR review, clinical trials at up to 5% show no significant irritancy or toxicity, though EWG flags it due to insufficient extensive safety data.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A versatile botanical extract that effectively plumps, brightens, and reduces wrinkles, suitable for most skin types.
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References
Sources