Science
Mechanism of Action
It increases Aquaporin-3 channels for water distribution and boosts Filaggrin and Involucrin synthesis to strengthen the skin barrier. Rich in polysaccharides, it promotes deep water retention.
Research
Clinical Evidence
High confidence3%
Key findings
- 01 Katekawa et al. (2020) showed a 90% increase in AQP3, 68% in FLG, and 51% in INV at 3%, leading to improved hydration and reduced TEWL.
- 02 Katekawa et al. (2020) demonstrated a significant reduction in transepidermal water loss (TEWL) in human volunteers at 1%.
- 03 Pessoa et al. (2012, 2015) reported accelerated neoangiogenesis and increased collagen in skin wounds at 5% (rat model).
Transparency
Dusting Analysis
No specific data regarding common dusting practices or misuse of this ingredient was found in the research.
The Formula
Formulation
Stability
This extract is typically supplied in a water/glycerin base and is stable within a pH range of 5.0-7.0. Store in a dark location to protect light-sensitive polyphenols.
Conflicts
- Strong oxidizers
- Highly alkaline environments
Safety
Safety Profile
Commonly used in commercial raw materials at 1-5%. Toxicology reviews indicate low toxicity for bark extracts; seeds contain bufotenine but bark preparations do not.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Anadenanthera Colubrina Bark Extract is a valuable ingredient for enhancing skin hydration and barrier function, supported by strong clinical evidence and broad skin type compatibility.
Related
Similar Ingredients
Finding similar ingredients…