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ANACARDOYL TRIPEPTIDE-1.

Valuable / ANTIOXIDANT, BLEACHING, SKIN PROTECTING

Anacardoyl Tripeptide-1 is a modified peptide combining Tripeptide-1 (GHK) with Anacardic Acid. It acts as a potent antioxidant and skin brightener, protecting against oxidative stress while reducing melanin production.

antioxidant skin brightening skin protecting

Science

This peptide derivative inhibits tyrosinase, an enzyme crucial for melanin synthesis, thereby achieving skin brightening. Additionally, it offers significant antioxidant protection, safeguarding skin cells from environmental damage.


Research

Medium confidence
Effective range 0.0001–0.003%
Optimal

N/A

Key findings

  1. 01 Cosmetic Ingredient Review (CIR) Safety Assessment of Tripeptide-1 and Related Amides (2014)

Transparency

Not commonly dusted

Peptides, especially modified derivatives, are typically effective at very low concentrations (parts per million), making them less prone to being used as 'dusting' ingredients.


The Formula

Solubility
Oil
Optimal pH 4 – 7
0 7 14

Stability

The anacardoyl fatty acid chain enhances lipophilicity, making it suitable for oil-based formulations. It maintains stability within a pH range of 4.0-7.0, with extreme pH levels potentially causing hydrolysis.

Conflicts

  • Strong oxidizing agents
  • Strong acids or bases
  • Proteolytic enzymes

Safety

CIR Status
Safe as used
Max tested
0.01%
Sensitization risk Low

The CIR Expert Panel concluded Tripeptide-1 and its derivatives, including Anacardoyl Tripeptide-1, are safe. The maximum reported concentration for the group in leave-on products is 1%.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

Anacardoyl Tripeptide-1 is a valuable ingredient for its dual action in brightening skin and providing robust antioxidant defense across all skin types.


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