Science
Mechanism of Action
This enzyme catalyzes the endo-hydrolysis of alpha-1,4-D-glycosidic bonds in starches. On the skin, it targets carbohydrate structures that bind dead cells and debris, enabling gentle exfoliation and pore cleansing.
Research
Clinical Evidence
Medium confidence2%
Key findings
- 01 INCIDecoder & Industry Manufacturer Guidelines (Reviderm, Atlantis Press)
- 02 Atlantis Press (IJCSE 2020)
Transparency
Dusting Analysis
No specific data suggests Amylase is commonly 'dusted' in cosmetic formulations, but optimal concentration for efficacy is well-defined.
The Formula
Formulation
Stability
Amylase is highly sensitive to pH and temperature, typically peaking activity at neutral pH (6.7-7.0) and denaturing above 40-50°C. It requires calcium ions for stability.
Conflicts
- Heavy metals (Hg2+, Cu2+, Zn2+)
- Strong oxidizing agents
- Chelating agents (EDTA) - if they remove essential calcium ions
- Extreme pH (<4.0 or >9.0)
Safety
Safety Profile
Amylase is not individually CIR reviewed, but related enzymes are often 'Safe as used'. It is considered a mild irritant only in high-concentration industrial settings and has GRAS status in food.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Amylase is a valuable enzyme for gentle exfoliation and skin conditioning, suitable for all skin types due to its low irritancy and comedogenicity.
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References
Sources