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AMYL OCTANOATE.

Valuable CAS 638-25-5 / PERFUMING

Amyl Octanoate is a versatile aliphatic ester functioning as an emollient and fragrance ingredient. It conditions the skin by forming a protective film and may also provide a cooling sensation.

Emollient Skin conditioning Perfuming Cooling agent

Science

This ester prevents transepidermal water loss by creating a non-greasy barrier on the skin. It also modulates TRPM8 cold-sensing ion channels, which can induce a cooling or chemesthetic effect.


Research

Medium confidence
Effective range 0.1–10%
Optimal

N/A

Key findings

  1. 01 US Patent 20090010958A1 / Poucher's Perfumes, Cosmetics and Soaps
  2. 02 Food and Cosmetics Toxicology, Vol. 18
  3. 03 EP3356356B1 - Compounds useful as modulators of TRPM8

Transparency

Not commonly dusted

As an oil-soluble ester, Amyl Octanoate is incorporated into formulations rather than dusted on top of them. It is not a powder-form ingredient.


The Formula

Solubility
Oil
Optimal pH 3 – 8.5
0 7 14

Stability

It is highly stable in oily and anhydrous systems. In emulsions, optimal stability is within pH 3.0-8.5; high alkalinity can cause hydrolysis.

Conflicts

  • Strong oxidizing agents
  • Strongly alkaline environments (pH > 10)
  • Strong acids

Safety

CIR Status
Not reviewed
Max tested
3%
Sensitization risk Low

While not individually reviewed by CIR, it belongs to ester groups generally recognized as safe by the FDA. ECHA reports no hazard classification.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Amyl Octanoate is a valuable, well-tolerated emollient and fragrance component that also offers a refreshing cooling sensation to the skin.


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