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AMYL ISOBUTYRATE.

Optional CAS 2445-72-9 / PERFUMING

A fruity-scented ester that serves as a masking agent in skincare formulations, providing apple-pear aromatic notes while neutralizing unpleasant ingredient odors. This synthetic fragrance compound is formed from amyl alcohol and isobutyric acid, offering sensory enhancement without direct therapeutic skin benefits.

perfuming masking

Science

Functions purely as an olfactory modifier by masking undesirable ingredient odors and imparting a pleasant fruity fragrance to formulations, with no direct biological activity on skin cells or therapeutic mechanisms.


Research

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 RIFM safety assessment established NESIL at 7000 μg/cm² for sensitization threshold
  2. 02 Detected at 0.2% in Psydrax plant extracts studied for antioxidant activity, though specific contribution unclear

Transparency

Not commonly dusted

As a fragrance component, typically used at minimal concentrations for sensory purposes rather than active therapeutic effects, making dusting unlikely.


The Formula

Solubility
Oil
Optimal pH 4 – 9
0 7 14

Stability

Susceptible to hydrolysis under extreme pH conditions, breaking down into constituent alcohol and acid components with resulting sour odor; most stable in balanced pH emulsions or anhydrous systems

Conflicts

  • Strong oxidizing agents
  • Strong acids
  • Strong bases

Safety

CIR Status
Not reviewed by CIR
Sensitization risk Low

RIFM-evaluated with established sensitization threshold; GRAS status for food use under FDA regulations (21 CFR 172.515) and FEMA approval


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Optional

A safe sensory modifier that enhances product experience through pleasant fragrance but offers no therapeutic skin benefits.


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