Science
Mechanism of Action
This extract acts primarily as an anti-inflammatory by inhibiting NF-κB activation and suppressing pro-inflammatory cytokines, iNOS, and COX-2 enzymes. Its high 1,8-cineole content reduces nitric oxide and prostaglandin E2 levels in the skin.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In vitro studies show fruit essential oil inhibits nitric oxide production and suppresses iNOS and COX-2 in LPS-stimulated macrophages.
- 02 Animal studies indicate seed extracts increase hypersensitivity reactions and stimulate immune responses, suggesting immunomodulatory activity.
Transparency
Dusting Analysis
No available data suggests this ingredient is commonly 'dusted' at sub-efficacious levels in cosmetic formulations.
The Formula
Formulation
Stability
Essential oil components are volatile and sensitive to heat and light. Ethanol or glycol-based extraction helps preserve beneficial polyphenol and terpene content.
Conflicts
- Strong oxidizing agents
- High heat during formulation (may degrade volatile aromatic compounds)
Safety
Safety Profile
While not formally reviewed by CIR, traditional use as a spice suggests a good safety profile. Contains Limonene and Linalool, which are potential allergens.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A valuable antioxidant and anti-inflammatory extract suitable for all skin types, offering soothing benefits and helping to reduce oxidative stress.
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