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Moumoujus

AMMONIUM THIOLACTATE.

Questionable CAS 13419-67-5 / DEPILATORY, HAIR WAVING OR STRAIGHTENING, REDUCING

A reducing agent containing a reactive sulfhydryl group primarily used in hair processing applications. While it can act as a keratolytic by weakening stratum corneum cell cohesion, its moderate sensitization potential and medium irritancy profile limit its use in precision skincare formulations.

Summary

reducing agent keratolytic hair processing aid

Science

Mechanism of Action

Functions as a reducing agent through its reactive sulfhydryl (-SH) group, breaking disulfide bonds in keratin structures and reducing intercellular cohesion in the stratum corneum to promote mild exfoliation

Research

Clinical Evidence

Medium confidence
Effective range 1–15.2%
Optimal

N/A

Key findings

  1. 01 German Contact Dermatitis Research Group study (n=177) found 4% sensitization rate at 2% concentration
  2. 02 Contact Dermatitis 2002 study demonstrated allergic contact dermatitis potential at 1% in repeated application testing

Transparency

Dusting Analysis

Not commonly dusted

Primarily used in hair processing rather than skincare; sensitization concerns limit cosmetic dusting applications

The Formula

Formulation

Solubility
Water
Optimal pH 7.5 – 9.5
0 7 14

Stability

Prone to oxidation forming diammonium dithiolactate; heat sensitive above 150°C with potential hydrogen sulfide evolution

Conflicts

  • Strong oxidizing agents
  • Hydrogen peroxide
  • Metal ions
  • Highly acidic environments

Safety

Safety Profile

CIR Status
Safe as used
Max tested
15.2%
Sensitization risk Moderate

CIR approval limited to rinse-off products when formulated to be non-irritating; leave-on skin applications discouraged due to sensitization potential

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

While technically effective as a keratolytic, the moderate sensitization risk and primary hair-focused applications make it unsuitable for precision skincare formulations.

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