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Moumoujus

AMMONIUM THIOCYANATE.

Questionable CAS 1762-95-4 / ANTIPERSPIRANT, BUFFERING, ORAL CARE, OXIDISING, REDUCING, VISCOSITY CONTROLLING

A multifunctional chemical compound that acts as a reducing agent, breaking disulfide bonds and controlling viscosity in cosmetic formulations. Primarily used in hair care products and antiperspirants, it demonstrates unique properties for dermo-epidermal interactions in specialized applications.

Summary

reducing buffering viscosity controlling oxidising antiperspirant

Science

Mechanism of Action

Functions primarily as a reducing agent by breaking disulfide bonds in proteins, while also serving as a buffering agent and viscosity controller. In specialized applications, it can disrupt basement membrane zone connections for dermo-epidermal separation.

Research

Clinical Evidence

Medium confidence
Effective range 3.8–10%
Optimal

5%

Key findings

  1. 01 3.8% concentration showed superior performance for dermo-epidermal separation while preserving RNA quality for transcriptomic analysis
  2. 02 5% concentration used as absorption tracer demonstrated 3.1-fold increased penetration when combined with 12.5% glycol stearate surfactant

Transparency

Dusting Analysis

Not commonly dusted

Primarily used in hair care and antiperspirant applications rather than skincare formulations, making dusting less relevant for facial skincare products

The Formula

Formulation

Solubility
Water
Optimal pH 4.5 – 6
0 7 14

Stability

Hygroscopic and light-sensitive compound that remains stable under normal conditions but decomposes at 170°C. Naturally maintains pH 4.5-6.0 in aqueous solutions.

Synergies

  • Glycol stearate surfactants

Conflicts

  • Strong acids
  • Strong oxidizing agents
  • Lead nitrate
  • Strong bases

Safety

Safety Profile

CIR Status
Not formally reviewed by CIR
Max tested
10%
Pregnancy
Caution
Sensitization risk Moderate

Australian NICNAS requires 'Caution' labels for concentrations above 10%. Recognized as potential irritant and thyroid inhibitor at high systemic doses. Can release toxic hydrogen cyanide gas when in contact with acids.

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

Limited skincare applications with moderate irritancy and safety concerns make it unsuitable for most precision skincare formulations.

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