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Moumoujus

AMMONIUM PROPIONATE.

Valuable CAS 17496-08-1 / PRESERVATIVE

Ammonium Propionate is an antimicrobial preservative highly effective in acidic environments, crucial for inhibiting the growth of bacteria and molds in skincare formulations. It also functions as a pH adjuster to maintain product integrity.

Summary

preservative pH adjuster

Science

Mechanism of Action

This ingredient functions by releasing undissociated propionic acid in acidic conditions, which penetrates microbial cell membranes. This process acidifies the cytoplasm and depletes intracellular ATP, thereby inhibiting microbial growth.

Research

Clinical Evidence

Medium confidence
Effective range 0.5–2%
Optimal

N/A

Key findings

  1. 01 A.M Foodchem Technical Data
  2. 02 EU Regulation (EC) No 1223/2009 Annex V

Transparency

Dusting Analysis

Not commonly dusted

As a preservative, ammonium propionate is integrated at concentrations necessary for microbial inhibition rather than for an active effect, so the concept of 'dusting' is not applicable.

The Formula

Formulation

Solubility
Water
Optimal pH 4 – 6.5
0 7 14

Stability

This ingredient is highly hygroscopic and deliquescent. It exhibits optimal stability and efficacy at lower pH levels, where it effectively releases free propionic acid.

Conflicts

  • strong oxidizing agents
  • strong bases
  • nitrosating agents

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
2%
Sensitization risk Moderate

While not individually reviewed by the CIR, EU Regulation (EC) No 1223/2009 allows a maximum concentration of 2% (calculated as propionic acid). Concentrated forms are classified as irritants.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Ammonium Propionate is a valuable preservative for acidic formulations, offering effective antimicrobial protection despite a moderate sensitization risk.

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