Science
Mechanism of Action
It stabilizes formulations by resisting changes in pH through its ionic dissociation into ammonium and phosphate ions. This buffering action is vital for maintaining product integrity and efficacy.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 Administration of diammonium phosphate in diet showed cariostatic effects, reducing the incidence and severity of dental caries in animal models (McClure, 1964).
- 02 In vitro studies evaluated its role in mitochondrial swelling and membrane porosity mechanisms as a source of phosphate ions (Sitaramam and Rao, 1992).
Transparency
Dusting Analysis
No specific data on dusting available for this ingredient in cosmetic applications.
The Formula
Formulation
Stability
Stable in aqueous solutions but can release trace ammonia over time, depending on the specific salt form. Optimal pH ranges vary, e.g., monobasic at 4.0-4.6 and dibasic at 7.8-8.9.
Conflicts
- Strong acids
- Strong bases
- Strong oxidizing agents
- Metal ions (Fe, Al, Mg)
Safety
Safety Profile
The CIR Expert Panel deemed it safe for cosmetic use if formulated to be non-irritating. The FDA also lists it as Generally Recognized as Safe (GRAS) for food.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Ammonium Phosphate is a valuable ingredient primarily for its pH buffering capabilities, ensuring product stability and mildness across all skin types.
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References
Sources