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Ingredient directory

Ammonium Nonoxynol-30 Sulfate

An anionic surfactant and emulsifying agent primarily utilized in rinse-off cleansing formulations for its ability to reduce water surface tension and facilitate oil-water mixing. The high ethoxylation number (30 units) creates a bulky molecular structure that limits skin penetration while maintaining effective cleansing properties. This ingredient serves as a functional backbone in hair care and facial cleansing products rather than an active treatment component.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

surfactant cleansing foaming emulsifying

Science

Functions by disrupting surface tension between water and lipid-based impurities, enabling the removal of oils, sebum, and debris from skin and hair surfaces through micelle formation and emulsification processes.


Research

Medium confidence
Effective range 2–5%
Optimal

5%

Key findings

  1. 01 Human repeat insult patch testing on related nonoxynols (1-8) demonstrated non-sensitizing properties at ≤5% concentrations, with increased allergic contact dermatitis risk at 10%+ levels
  2. 02 Clinical assessment of similar ethoxylated surfactants showed 2% sensitization rate specifically in dermatitis-predisposed populations

Transparency

Not commonly dusted

As a functional surfactant ingredient rather than an active component, dusting is not applicable to this cleansing agent.


The Formula

Solubility
Water
Optimal pH 5 – 8
0 7 14

Stability

Demonstrates high stability in neutral to mildly alkaline aqueous environments, with potential sulfate group hydrolysis under extreme acidic conditions or elevated temperatures.

Conflicts

  • Cationic surfactants
  • Strongly acidic environments (pH < 3.0)
  • Polyvalent metal ions

Safety

CIR Status
Safe as used
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

CIR Expert Panel established safety for rinse-off applications with leave-on product safety confirmed up to 5% concentration based on irritation potential assessment.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Optional

A reliable functional surfactant for rinse-off applications with established safety profile, though not essential given availability of alternative cleansing agents.


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References

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