Science
Mechanism of Action
Creates a hygroscopic film on the skin surface using low molecular weight peptides that actively bind water to the stratum corneum, reducing transepidermal water loss (TEWL) while improving skin suppleness and hydration retention
Research
Clinical Evidence
Medium confidence0.12%
Key findings
- 01 CIR Expert Panel assessment established maximum safe use concentration of 0.12% based on industry surveys (2017)
- 02 Parent compound (hydrolyzed collagen) demonstrated non-irritating properties at concentrations up to 50% and non-sensitizing at 20% in HRIPT testing
Transparency
Dusting Analysis
Used at very low concentrations (0.12% maximum) making dusting unlikely; functions effectively at established percentages
The Formula
Formulation
Stability
Highly water-soluble with reduced viscosity compared to native collagen; stable across temperature ranges but sensitive to extreme pH variations which can disrupt protein structure; lower isoelectric point (3.68-5.7) than native collagen
Synergies
- hyaluronic acid
- glycerin
- ceramides
Conflicts
- strong oxidizing agents
- high concentrations of anionic surfactants
- formulations outside pH 4-7 range
Safety
Safety Profile
CIR Expert Panel concluded safety in current usage practices; fish-derived sources may require allergy warnings for Type I hypersensitivity individuals
Your Skin
Skin Compatibility
Our Assessment
Verdict
A well-tolerated, multi-functional humectant with proven safety profile and universal skin type compatibility at established concentrations.
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