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AMMONIUM HYDROLYZED COLLAGEN.

Valuable CAS 222400-34-2 / ANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

A water-soluble, modified form of collagen peptides that delivers enhanced humectant properties through low molecular weight protein fragments (3-6 kDa). The ammonium salt modification improves solubility and film-forming capabilities compared to standard collagen derivatives. Functions primarily as a moisture-binding agent that creates a protective film on skin to reduce water loss.

humectant skin conditioning film forming antistatic

Science

Creates a hygroscopic film on the skin surface using low molecular weight peptides that actively bind water to the stratum corneum, reducing transepidermal water loss (TEWL) while improving skin suppleness and hydration retention


Research

Medium confidence
Effective range 0.01–0.12%
Optimal

0.12%

Key findings

  1. 01 CIR Expert Panel assessment established maximum safe use concentration of 0.12% based on industry surveys (2017)
  2. 02 Parent compound (hydrolyzed collagen) demonstrated non-irritating properties at concentrations up to 50% and non-sensitizing at 20% in HRIPT testing

Transparency

Not commonly dusted

Used at very low concentrations (0.12% maximum) making dusting unlikely; functions effectively at established percentages


The Formula

Solubility
Water
Optimal pH 5 – 6.5
0 7 14

Stability

Highly water-soluble with reduced viscosity compared to native collagen; stable across temperature ranges but sensitive to extreme pH variations which can disrupt protein structure; lower isoelectric point (3.68-5.7) than native collagen

Synergies

  • hyaluronic acid
  • glycerin
  • ceramides

Conflicts

  • strong oxidizing agents
  • high concentrations of anionic surfactants
  • formulations outside pH 4-7 range

Safety

CIR Status
Safe as used
Max tested
0.12%
Pregnancy
Safe
Sensitization risk Low

CIR Expert Panel concluded safety in current usage practices; fish-derived sources may require allergy warnings for Type I hypersensitivity individuals


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A well-tolerated, multi-functional humectant with proven safety profile and universal skin type compatibility at established concentrations.


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