Science
Mechanism of Action
Forms a flexible proteinaceous film on the skin surface that reduces transepidermal water loss while supplying amino acids that integrate into the skin's natural moisturizing factor network. Additionally stabilizes emulsion systems by reducing surface tension at oil-water interfaces.
Research
Clinical Evidence
High confidence2%
Key findings
- 01 Demonstrated non-sensitizing and non-irritating properties in clinical assessments of milk proteins at 2% concentration in leave-on formulations
- 02 Related casein derivatives showed negative results for irritation and sensitization at concentrations up to 30%, supporting safety profile
Transparency
Dusting Analysis
Not commonly used as a dusting ingredient in cosmetic formulations due to its primary functions as film-former and skin conditioner
The Formula
Formulation
Stability
Requires near-neutral to alkaline pH for stability; precipitates at isoelectric point around pH 4.6 causing formula separation
Synergies
- Neutral to alkaline pH buffers
- Water-soluble humectants
- Anionic and nonionic surfactants
Conflicts
- Acids below pH 5.0
- Cationic surfactants
- Heavy metal ions
- High concentrations of calcium salts
Safety
Safety Profile
CIR Expert Panel concluded safety for cosmetic use; potential food allergen (bovine milk) but not considered sensitization risk in topical applications
Your Skin
Skin Compatibility
Our Assessment
Verdict
Well-researched milk protein derivative offering reliable skin conditioning and barrier support with excellent safety profile across all skin types.
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References
Sources