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Moumoujus

AMMONIUM BETA-SITOSTERYL SULFATE.

Valuable / HAIR CONDITIONING, SKIN CONDITIONING

A water-compatible derivative of the plant sterol beta-sitosterol that has been sulfated and neutralized with ammonia to enhance its conditioning properties. This biomimetic lipid mimics cholesterol sulfate naturally found in skin's outer layer, helping to reinforce barrier function and regulate cellular turnover. Its dual water-oil compatibility makes it particularly valuable for stabilizing emulsions and improving product delivery.

Summary

skin conditioning hair conditioning emulsion stabilizing barrier repair

Science

Mechanism of Action

Functions as a biomimetic barrier lipid that integrates into skin's lipid bilayers, mimicking the role of natural cholesterol sulfate in the stratum corneum. The sulfate group provides surfactant-like properties that help stabilize cellular membranes while regulating desquamation and maintaining structural integrity to prevent transepidermal water loss.

Research

Clinical Evidence

Medium confidence
Effective range 0.1–1%
Optimal

0.5%

Key findings

  1. 01 Beta-sitosteryl sulfate demonstrated significant reduction in liposomal particle size with improved dispersibility and enhanced hydration in vitro

Transparency

Dusting Analysis

Not commonly dusted

Specialized ingredient with specific barrier repair functions, unlikely to be used in cosmetically insignificant amounts

The Formula

Formulation

Solubility
Both
Optimal pH 5 – 7.5
0 7 14

Stability

More water-dispersible than parent beta-sitosterol due to ammonium salt structure. Stable under neutral to mildly acidic conditions but may hydrolyze or release ammonia above pH 8.0

Synergies

  • Other barrier lipids
  • Cholesterol
  • Ceramides
  • Liposomal delivery systems

Conflicts

  • Strongly alkaline ingredients
  • Cationic surfactants
  • Strong oxidizing agents

Safety

Safety Profile

CIR Status
Safe as used
Max tested
1%
Pregnancy
Safe
Sensitization risk Low

Reviewed under phytosterol derivatives class by CIR Expert Panel with conclusion of safety in current usage practices

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A well-tolerated biomimetic barrier lipid that offers enhanced water compatibility and proven membrane-stabilizing benefits for all skin types.

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