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AMINOTRIMETHYLENE PHOSPHONIC ACID.

Valuable CAS 6419-19-8 / CHELATING

Aminotrimethylene Phosphonic Acid (ATMP) is a robust chelating agent vital for stabilizing cosmetic formulations. It safeguards product integrity by sequestering metal ions that can catalyze oxidation and degrade active ingredients.

Summary

chelating

Science

Mechanism of Action

ATMP functions by tightly binding to transition metal ions such as iron, copper, and zinc. This action prevents metal-induced oxidative damage and inhibits the precipitation of metal salts, thereby maintaining formula color, scent, and ingredient stability.

Research

Clinical Evidence

Medium confidence
Effective range 0.001–1%
Optimal

N/A

Key findings

  1. 01 US Patent 10729667B2; International Cosmetic Ingredient Dictionary and Handbook

Transparency

Dusting Analysis

Not commonly dusted

Data not available to determine if this ingredient is commonly dusted.

The Formula

Formulation

Solubility
Water
Optimal pH 2 – 12
0 7 14

Stability

Highly stable across a broad pH and temperature range, ATMP resists hydrolysis even under harsh conditions and remains effective in both acidic and alkaline environments.

Conflicts

  • Strong oxidizing agents
  • Bases (in concentrated acid form)

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Low

While not formally reviewed by CIR, ATMP is listed in the EU CosIng database. Concentrated forms can be irritating, but it is considered safe at the low concentrations typically used in finished cosmetic products.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Aminotrimethylene Phosphonic Acid is a valuable chelating agent essential for enhancing formula stability, preventing oxidation, and maintaining the efficacy of other ingredients.

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