Science
Mechanism of Action
This ingredient functionally mimics the OGG1 enzyme, recognizing and facilitating the excision of 8-oxoguanine lesions, a major mutagenic base caused by UV exposure. This process supports the skin's natural base excision repair (BER) pathway, actively preventing photo-aging.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Clinical observations of products containing 0.1% to 0.5% Aminopentyl Guanine demonstrated significant reduction in 8-oxoguanine (a DNA damage marker), along with improved skin elasticity and overall photo-damaged appearance.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Highly stable in aqueous solutions at neutral pH. While sensitive to extreme hydrolytic conditions, it maintains stability in typical cosmetic emulsions.
Conflicts
- Strong oxidizing agents
- Extreme acidic conditions (pH < 4.0)
Safety
Safety Profile
Although not formally reviewed by the CIR, Aminopentyl Guanine is listed in the EU CosIng database and PCPC inventory. It is generally considered safe in professional use concentrations, typically below 1.0%.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A valuable ingredient for targeted photo-damage repair and antioxidant protection, enhancing skin resilience across all skin types.
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References
Sources