Science
Mechanism of Action
As a direct precursor to Creatine, Amidinoglycine boosts cellular ATP homeostasis, acting as an energy enhancer for skin cells. It promotes collagen synthesis, accelerates cell renewal via the HaCaT pathway, and reduces inflammatory biomarkers like IL-1a.
Research
Clinical Evidence
High confidence1%
Key findings
- 01 A 1.0% concentration significantly reduced skin redness and irritation, and accelerated skin repair by boosting HSP-27 and decreasing IL-1a.
- 02 Effective concentrations between 0.1% and 20.0% have been cited for inhibiting aging damage and preserving skin in topical formulations.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Highly stable in aqueous solutions within physiological pH; it is zwitterionic at neutral pH but susceptible to acid hydrolysis at very low pH.
Conflicts
- Strong oxidizing agents
- Extremely acidic environments (pH < 3.0)
Safety
Safety Profile
Reviewed under 'Amino Acid Alkyl Amides', the CIR Expert Panel found it safe when formulated to be non-irritating.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Amidinoglycine is a valuable ingredient for advanced skincare, offering cellular energy support, anti-aging benefits, and soothing properties with excellent skin compatibility and a low risk profile.
Related
Similar Ingredients
Finding similar ingredients…