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Moumoujus

AMBRETTOLIDE.

Valuable CAS 7779-50-2 / PERFUMING

Ambrettolide is a macrocyclic musk widely valued for its sensory profile, enhancing fragrance diffusion and fixative properties in formulations. It also offers a smoothing emollient effect on the skin without deep penetration.

Summary

Perfuming Fragrance fixative Emollient

Science

Mechanism of Action

This macrocyclic musk primarily acts as a fragrance fixative, slowing volatile scent evaporation and rounding out olfactory profiles. On the skin, its oily nature provides a surface smoothing, emollient effect.

Research

Clinical Evidence

High confidence
Effective range 0.01–5%
Optimal

N/A

Key findings

  1. 01 Enhances fragrance diffusion and fixative properties; suitable for acne-prone skin due to low comedogenicity (rating 1).
  2. 02 Demonstrated high stability and longevity (up to 1 month) in various cosmetic bases.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH 3.5 – 9
0 7 14

Stability

Stable in alcoholic solutions and most cosmetic bases. Stability decreases significantly in highly acidic (pH < 3) or highly alkaline (pH > 11) environments.

Conflicts

  • Strong oxidizing agents
  • Liquid bleach
  • Highly acidic formulations

Safety

Safety Profile

CIR Status
Safe as used
Max tested
5%
Sensitization risk Low

Distinguished from restricted 'Musk Ambrette'; it is non-sensitizing and non-phototoxic with a NOAEL of 1000 mg/kg/day.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A valuable ingredient for enhancing product sensory profiles and stability, offering a gentle emollient effect suitable for all skin types, including acne-prone.

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