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Moumoujus

AMBERGRIS EXTRACT.

Questionable CAS 84836-94-2 / PERFUMING

Historically used for skin and hair health, Ambergris Extract is valued for its potential in tissue regeneration and as a fixative. Its bioactive components like ambrein offer antioxidant and anti-inflammatory benefits.

Summary

perfuming skin conditioning antioxidant anti-inflammatory regenerative

Science

Mechanism of Action

Ambergris primarily functions as a high-affinity fixative, slowing the evaporation of volatile compounds. Its ambrein and epicoprostanol constituents exert antioxidant, anti-inflammatory, and potential tissue-regenerative effects by modulating cellular processes.

Research

Clinical Evidence

Low confidence
Effective range 3–3%
Optimal

3%

Key findings

  1. 01 A historical cosmetic formulation used at 3.0% was noted for promoting tissue regeneration and prolonging scent duration.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH 4 – 8
0 7 14

Stability

Highly stable and oxidation-resistant once aged, it acts as a stabilizer for other volatile components. Best dissolved in ethanol or fixed oils.

Conflicts

  • Water-based systems (requires solubilizers)
  • Strong oxidizing agents

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
3%
Sensitization risk Low

While not reviewed by CIR for skincare, RIFM monographs exist for fragrance use. Its use is largely restricted due to CITES and sperm whale protection, favoring synthetic alternatives like Ambroxan.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

Ambergris Extract offers historical skin conditioning and regenerative claims, but its use is complicated by ethical concerns and a lack of modern topical efficacy studies.

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