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AMARANTHUS HYPOCHONDRIACUS SEED OIL.

Valuable CAS 90320-45-9 / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Amaranthus Hypochondriacus Seed Oil is a biomimetic emollient exceptionally rich in squalene, closely matching human sebum. It effectively reinforces the skin barrier, enhances hydration, and provides antioxidant protection.

emollient antioxidant skin-identical ingredient

Science

This oil acts as a skin-identical ingredient, delivering 6-8% squalene to strengthen the stratum corneum lipid barrier, preventing transepidermal water loss. It also provides antioxidant defense through Vitamin E, phytosterols, and activates the Nrf2 pathway to protect fibroblasts from UVA-induced oxidative stress.


Research

High confidence
Effective range 0.1–100%
Optimal

N/A

Key findings

  1. 01 An in vitro study showed that 0.1-0.15% concentration significantly decreased pro-apoptotic proteins and improved cell survival in UVA-treated human skin fibroblasts.
  2. 02 Topical application of pure oil (100%) for 28 days significantly improved skin hydration and reduced roughness/scaling in participants with xerosis.

Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH 4 – 7
0 7 14

Stability

Its high squalene and unsaturated fatty acid content make it susceptible to lipid peroxidation. Stability is improved by adding antioxidants (e.g., tocopherol) or using airtight, light-protected packaging.

Synergies

  • Antioxidants (e.g., tocopherol)

Conflicts

  • Strong oxidizing agents
  • High heat (>300°C)
  • Prolonged exposure to light and air

Safety

CIR Status
Safe as used
Max tested
100%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) expert panel has evaluated it as safe for cosmetic use, and it is also classified as Generally Recognized As Safe (GRAS) for consumption.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Amaranthus Hypochondriacus Seed Oil is a highly valuable ingredient for barrier repair, intense hydration, and potent antioxidant protection, compatible with all skin types.


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