Science
Mechanism of Action
It diffuses into eccrine sweat glands, forming a polymeric gel-like plug in the sweat duct upon contact with sweat and a pH change. This colloidal plug physically blocks perspiration, eventually shedding naturally through the skin's keratinization.
Research
Clinical Evidence
High confidence20%
Key findings
- 01 Regular application of 20% aluminum salts provides 20-60% sweat reduction, with significant increases in efficacy during initial application.
- 02 Clinical evaluation of formulations with 20% Aluminum Zirconium complexes showed effective reduction of axillary sweat and body odor within less than a week.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Zirconium species can precipitate at higher pH; stability is improved by adding amino acids like Glycine and maintaining low metal-to-chloride ratios (0.9–1.25).
Conflicts
- Alkaline ingredients (cause precipitation)
- Strong oxidizing agents
- Certain anionic surfactants (may cause complexation)
Safety
Safety Profile
The FDA classifies it as safe and effective for OTC antiperspirants, while the EU restricts it to 20% concentration (5.4% as zirconium). Avoid application on irritated or damaged skin.
Your Skin
Skin Compatibility
Our Assessment
Verdict
ALUMINUM ZIRCONIUM PENTACHLOROHYDRATE is a valuable antiperspirant ingredient, highly effective at reducing sweat and odor for most skin types.
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References
Sources