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Moumoujus

ALUMINUM FLUORIDE.

Insufficient Data CAS 7784-18-1 / ANTIPLAQUE, ORAL CARE

Aluminum Fluoride is an inorganic compound primarily recognized for its role in oral hygiene. It functions as a source of fluoride ions, with broader biochemical interactions as a phosphate analog.

Summary

anti-caries oral care agent

Science

Mechanism of Action

It primarily works by releasing fluoride ions that integrate into tooth enamel, enhancing acid resistance and remineralization. Biochemically, aluminofluoride complexes can mimic phosphates, interacting with G proteins to influence cellular signaling pathways.

Research

Clinical Evidence

High confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 SCCS Opinion on Fluorine Compounds in Oral Hygiene Products (SCCNFP/0653/03)

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 4 – 8
0 7 14

Stability

Sparingly soluble in water (0.5-0.6 g/100 mL at 25°C), stability is maintained within typical physiological pH ranges in aqueous systems. Moisture can affect it, with hydrolysis at very high temperatures releasing hydrogen fluoride.

Conflicts

  • Alkali metals
  • Strong acids
  • Superheated steam

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
0.15%
Sensitization risk Low

The 0.15% limit is specifically for oral hygiene products, calculated as Fluorine content, and is regulated under EU Cosmetic Regulation Annex III. Its safety profile for dermal application is not extensively reviewed.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Despite its established efficacy in oral care, there is insufficient data regarding Aluminum Fluoride's benefits or specific applications in precision skincare formulations.

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References

Sources