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ALUMINUM DIACETATE.

Valuable CAS 142-03-0 / ANTIMICROBIAL, ASTRINGENT

Aluminum Diacetate is a metallic salt primarily recognized for its potent topical astringent properties. It is FDA-approved for use in OTC skin protectant products, offering relief for minor skin irritations and reducing inflammation.

astringent antimicrobial

Science

It functions by inducing mild coagulation of skin proteins and constricting tissues, facilitating water removal from the application site. This action reduces inflammation, itching, and exudation, particularly in wet skin lesions.


Research

High confidence
Effective range 0.13–0.5%
Optimal

0.5%

Key findings

  1. 01 The FDA designates 0.13%-0.5% as the approved concentration range for OTC skin protectants, effective as an astringent.
  2. 02 Studies indicate extremely low systemic absorption of aluminum following topical application, averaging 0.0094%.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 3.8 – 4.6
0 7 14

Stability

Most stable in acidic conditions (pH 3.8-4.6); typically requires stabilization with boric acid to prevent aluminum hydroxide precipitation. Stable at room temperature.

Conflicts

  • Strong oxidizing agents
  • Alkali hydroxides
  • Carbonates
  • Phosphates

Safety

CIR Status
Not reviewed
Max tested
0.5%
Sensitization risk Low

While CIR has not reviewed it, FDA permits its use up to 0.5% in OTC skin protectants. SCCS deems aluminum compounds generally safe in non-sprayable cosmetics, and it is not classified as a CMR substance.


Your Skin

Yes Normal
No Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An FDA-approved topical astringent with mild antimicrobial properties, valuable for managing minor skin irritations, especially on oily and normal skin, due to its efficacy and low absorption rate.


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