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Moumoujus

ALUMINUM CHLOROHYDREX.

Valuable CAS 53026-85-0 / 68953-68-4 / ANTIPERSPIRANT, ASTRINGENT, DEODORANT

Aluminum Chlorohydrex functions as an effective antiperspirant and astringent, primarily reducing sweat flow. It is well-regarded for its tolerability in managing hyperhidrosis and temporarily constricting pores.

Summary

antiperspirant astringent

Science

Mechanism of Action

This ingredient forms a temporary colloidal gel plug within sweat gland ducts by precipitating aluminum ions with proteins and mucopolysaccharides. This physical obstruction effectively diminishes sweat release to the skin surface, acting as an antiperspirant.

Research

Clinical Evidence

High confidence
Effective range 20–21%
Optimal

20%

Key findings

  1. 01 A 20% concentration demonstrated similar efficacy to aluminum chloride in treating primary axillary hyperhidrosis, with improved tolerability and less irritation.
  2. 02 Dermal absorption studies at 21% showed only 0.012% absorption, indicating no significant contribution to systemic aluminum body burden.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 3 – 5
0 7 14

Stability

Stability is highly pH-dependent; pH values above 5.0 can induce precipitation of insoluble aluminum hydroxide. Complexing with PEG or PG can enhance stability in anhydrous systems.

Conflicts

  • Phosphate buffers
  • Citrate buffers
  • Strongly alkaline ingredients
  • Certain anionic surfactants

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
25%
Sensitization risk Low

The FDA OTC Monograph permits concentrations up to 25% in anhydrous forms. SCCS (2023) considers aluminum salts safe in non-sprayable products, allowing up to 10.60% as elemental aluminum.

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Aluminum Chlorohydrex is a highly effective antiperspirant and astringent, well-tolerated and with minimal systemic absorption, making it valuable for sweat control and pore refinement.

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