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Moumoujus

ALPHA-CEDRENE.

Questionable CAS 469-61-4 / PERFUMING

Alpha-cedrene is a naturally occurring bicyclic sesquiterpene, primarily utilized in cosmetic formulations for its ability to stabilize and extend the longevity of scents. It helps to maintain the aromatic profile of products over time.

Summary

Perfuming Fragrance Fixative Antimicrobial

Science

Mechanism of Action

Alpha-cedrene functions predominantly as a fragrance fixative, enhancing and prolonging the stability of scents in personal care items. It also exhibits mild antimicrobial properties, which can contribute to product integrity.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

Alpha-cedrene is primarily a fragrance ingredient and fixative, not commonly marketed as a standalone active ingredient with specific efficacy claims, thus not typically subject to 'dusting' concerns.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Alpha-cedrene exhibits stability under standard storage conditions. However, as a terpene, it is prone to oxidation and subsequent polymerization upon prolonged air exposure. For optimal product stability, it should be stored in a cool, dry, well-ventilated area, protected from light, and high temperatures should be avoided to prevent decomposition or volatilization.

Conflicts

  • Oxidizing agents (e.g., nitrates, oxidizing acids, chlorine bleaches, pool chlorine)
  • Heat, sparks, open flames, and all sources of ignition
  • Rags wet with unsaturated hydrocarbons/drying oils (may auto-oxidize, become self-heating, and ignite)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

Alpha-cedrene is classified as a flammable liquid and has the potential to cause skin and eye irritation. A rabbit skin irritation study at 500 mg/24h resulted in moderate irritation. The International Fragrance Association (IFRA) 51st amendment restricts its use due to concerns over dermal sensitization. Maximum permitted concentrations vary significantly by product category: for instance, 0.27% for lip products, 0.08% for axillary products, 0.38% for leave-on products applied to the face or body, and 1.6% for products applied to the face/body using fingertips. Despite human experience showing no irritation or sensitization with a 5% solution, the IFRA restrictions underscore a recognized risk, particularly for predisposed individuals.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

Primarily functioning as a fragrance fixative with mild antimicrobial properties, alpha-cedrene presents a moderate risk of dermal sensitization and lacks direct, proven skin-specific efficacy, making its role in precision skincare formulations debatable.

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