Science
Mechanism of Action
Its polysaccharides act as humectants to bind moisture, while C-glucosyl chromone and salicylates provide anti-inflammatory effects. Glucomannans stimulate fibroblast growth factor receptors, promoting collagen synthesis and wound healing.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Significantly improved clinical signs of psoriasis with an 83% cure rate in a double-blind, placebo-controlled study (Syed et al., 1996).
- 02 Increased the antioxidant capacity of the skin due to protective flavonoid and phenolic content (NIH, 2023).
- 03 Acemannan, a key polysaccharide, stimulated fibroblast proliferation and collagen synthesis in vitro (Jettanacheawchankit et al., 2009).
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Highly sensitive to heat and light; cold-processing or high hydrostatic pressure is preferred to maintain bioactive integrity. Its electrolyte content may reduce carbomer-based gel viscosity.
Conflicts
- Strong oxidizing agents
- High concentrations of alcohol (risk of polysaccharide precipitation)
- Carbomer (due to electrolyte sensitivity)
Safety
Safety Profile
The CIR Expert Panel deems it safe when anthraquinone (aloin) levels are kept below 50 ppm to avoid potential phototoxicity and irritation.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A highly versatile ingredient, Aloe Barbadensis Leaf Extract delivers significant soothing, hydrating, and regenerative benefits across various skin types with a favorable safety profile.
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References
Sources