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ALOE ARBORESCENS LEAF PROTOPLASTS.

Valuable CAS 223747-76-0 / HUMECTANT, SKIN CONDITIONING

Aloe Arborescens Leaf Protoplasts visibly enhance skin's youthful appearance by stimulating collagen production and soothing the complexion. This ingredient offers multi-faceted benefits for aging and sensitive skin types.

skin conditioning soothing moisturizing

Science

Rich in barbaloin and low-molecular-weight polysaccharides, it stimulates fibroblast proliferation and collagen synthesis. It also inhibits matrix metalloproteinase-1 (MMP-1), an enzyme that degrades collagen, and provides antioxidant protection through phenolic compounds.


Research

Medium confidence
Effective range 0.1–1%
Optimal

N/A

Key findings

  1. 01 In vitro studies at 0.5% activated human fibroblast cells by up to 175%, promoting collagen synthesis and inhibiting MMP-1 degradation.
  2. 02 Concentrations from 0.1% to 1% induced significant increases (10–20%) in collagen synthesis and effectively inhibited enzymatic activity related to skin aging.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 4 – 6.5
0 7 14

Stability

Most stable at room temperature (approx. 27°C); higher temperatures (>40°C) can cause pH shifts and degrade bioactive components, leading to color changes.

Conflicts

  • Strongly alkaline environments (pH > 7.0)
  • High heat during processing
  • Strong oxidizing agents

Safety

CIR Status
Insufficient data
Max tested
20%
Sensitization risk Low

The CIR Expert Panel found insufficient data for Aloe arborescens leaf derivatives due to unclear characterization. Industry standards mandate anthraquinone levels must remain below 50 ppm to prevent phototoxicity.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

This ingredient is valuable for anti-aging and soothing formulations, demonstrating significant collagen-boosting and protective properties across various skin types.


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