Science
Mechanism of Action
This extract stimulates fibroblast activation and collagen synthesis while effectively inhibiting Matrix Metalloproteinase-1 (MMP-1) to reduce collagen degradation. It also provides antioxidant defense through free radical scavenging, offers anti-inflammatory benefits, and delivers humectant and emollient properties via polysaccharides.
Research
Clinical Evidence
Medium confidence0.5%
Key findings
- 01 0.5% lactic acid fermented extract significantly boosted fibroblast activation (up to 175%) and collagen production (up to 170%), alongside 48% MMP-1 inhibition.
- 02 Non-fermented extract (0.5%) showed 140% fibroblast activation and 80% antioxidant activity (DPPH scavenging).
- 03 Extracts containing anthraquinones (1.0%-2.0%) demonstrated effective UV radiation screening, absorbing maximally around 294 nm (UVB).
- 04 Whole leaf extract (0.07-1.13 mg/mL) exhibited potent antibacterial and high antioxidant activity, surpassing other aloe species.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Highly sensitive to temperature, best stable between 4°C-27°C. Alkaline pH (>7.0) can cause color changes due to betacyanin instability, and polysaccharides are sensitive to high shear and electrolytes.
Conflicts
- Strongly alkaline ingredients (pH > 7.0)
- Strong oxidizing agents
- High concentrations of electrolytes/salts
Safety
Safety Profile
The CIR Expert Panel noted insufficient data for A. arborescens specifically, requesting 28-day dermal toxicity studies. Anthraquinone levels, such as aloin, must be below 50 ppm to avoid phototoxicity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A valuable ingredient for its robust anti-aging, antioxidant, and soothing properties, though further safety data on anthraquinone levels is requested by regulatory bodies.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources