Science
Mechanism of Action
Its efficacy relies on allicin and sulfur compounds, which provide antimicrobial and antioxidant protection by neutralizing free radicals. It also mitigates inflammation by reducing cytokines (TNF-α, IL-6), supports regeneration, and promotes brightening.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 0.4% Diallyl trisulfide (DATS) significantly reduced erlotinib-induced skin toxicities and inflammatory injury (lowered TNF-α, IL-6) in mouse models.
- 02 0.1% demonstrated a significant inhibitory effect against MRSA and other pathogens, particularly in wound healing contexts.
- 03 Topical applications of garlic extract/oil up to 5.0% have been investigated for improving conditions like psoriasis, alopecia areata, and keloid scars.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Optimal stability for allicin is observed at pH 5-6, with degradation occurring above 40°C or at extreme pH values (below 1.5, above 11.0). Encapsulation is typically required to address its low stability and strong characteristic odor.
Conflicts
- High temperature processes
- Strongly alkaline environments
- Strongly acidic environments
Safety
Safety Profile
The FDA classifies Garlic Oil as GRAS for food use. While it exhibits low toxicity in cosmetic applications, its potent odor often necessitates the use of masking agents.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Allium Sativum Bulb Oil is a valuable ingredient, delivering proven antimicrobial, antioxidant, and anti-inflammatory benefits with low irritation and comedogenicity.
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References
Sources