Science
Mechanism of Action
Its efficacy stems from organosulfur compounds like alliin and flavonoids such as kaempferol and quercetin, which scavenge free radicals and inhibit pro-inflammatory cytokines like IL-6. Pectic polysaccharides and alpha-linolenic acid further support skin barrier hydration.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In vitro studies (5 μg/mL) suggest anti-inflammatory and anti-allergic potential by modulating epithelial function and reducing IL-6 secretion and mast cell degranulation.
- 02 A pilot topical human trial demonstrated efficacy in symptomatic reduction for hemorrhoids, though a standard concentration for general skincare use was not defined.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Bioactive compounds are heat-sensitive, degrading above 60°C. Optimal stability is within a neutral to slightly acidic pH range (5.0-7.0), as high alkalinity (pH > 9) can destabilize components.
Conflicts
- Strong oxidizing agents
- High heat during processing
- Highly alkaline environments (pH > 8.0)
Safety
Safety Profile
Generally considered non-irritating and low cytotoxicity (up to 50 mg/mL in vitro), as a common food-derived ingredient. Topical safety limits are still emerging.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A valuable antioxidant and anti-inflammatory ingredient, suitable for all skin types, supporting skin barrier health and soothing irritation.
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References
Sources