Science
Mechanism of Action
This oil provides Omega-3, 6, 9, and oleic acid, acting as emollients to reduce transepidermal water loss. It modulates TGF-β1/Smad3 pathways to inhibit excessive collagen deposition and suppresses pro-inflammatory cytokines via p38 MAPK and NF-κB pathways.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In vitro, 0.125-2.0% concentrations demonstrated anti-inflammatory effects by reducing IL-6 and inhibiting NF-κB signaling.
- 02 A rat model showed 100% oil accelerated deep burn wound healing and reduced scar formation by downregulating TGF-β1 expression.
- 03 Human clinical testing of a lotion indicated improved skin hydration and barrier function, though some elasticity benefits were not observed.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Exhibits good stability for over 6 months in emulsion forms, with optimal stability observed within a pH range of 4.0–7.5.
Conflicts
- Strong oxidizing agents
- High heat (risk of rancidity)
Safety
Safety Profile
This ingredient has a history in traditional medicine and is generally marketed as hypoallergenic. Formal review by CIR or SCCS is currently pending.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A multifaceted ingredient offering significant emollient, anti-inflammatory, and wound healing benefits across various skin types with low irritation risk.
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References
Sources