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ALANINE GLUTAMATE.

Valuable CAS 13187-90-1 / SKIN CONDITIONING

Alanine Glutamate is a precision dipeptide, meticulously engineered from alanine and glutamic acid to optimize skin hydration and strengthen the dermal barrier. This ingredient delivers multi-functional benefits, enhancing skin conditioning and supporting its natural resilience.

Skin-Conditioning Agent Humectant Barrier Support Collagen Synthesis Support

Science

Functioning primarily as a humectant and skin-conditioning agent, Alanine Glutamate effectively attracts and retains moisture within the stratum corneum, leading to significantly improved skin hydration. Its constituent amino acids, alanine and glutamic acid, are critical for this moisture retention, supporting a robust skin barrier. Additionally, alanine is known to contribute to collagen synthesis, vital for maintaining skin structure and elasticity.


Research

Medium confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Alanine Glutamate is readily soluble in water, facilitating its integration into aqueous formulations. While a specific optimal pH range for the dipeptide's stability has not been explicitly defined, the pKa values of its glutamic acid component suggest potential changes in protonation state around pH 4.07, with physiological pH ranges of 7.35-7.45 also being relevant for its activity.


Safety

CIR Status
Safe as used
Sensitization risk Low

The safety of Alanine Glutamate is well-supported, primarily through the established safety of its individual amino acid components. The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that alpha-amino acids, including alanine and glutamic acid, are safe in current cosmetic uses. Furthermore, L-amino acids are generally recognized as safe (GRAS) by the FDA as direct food additives, reinforcing the benign profile of this dipeptide.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Alanine Glutamate is a valuable ingredient, offering precise hydration, enhanced barrier function, and support for skin elasticity, suitable for all skin types and diverse skincare applications.


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