Science
Mechanism of Action
It actively inhibits Advanced Glycation End-products (AGEs) and reduces Reactive Oxygen Species (ROS), thereby preventing collagen stiffening and degradation. Additionally, it contains saponins that boost urea production, contributing to Natural Moisturizing Factors (NMF) in the epidermis.
Research
Clinical Evidence
High confidence2%
Key findings
- 01 At 1.0%-2.0%, clinical studies showed significant anti-glycation by reducing CML and stimulating fibrillin-1, leading to a visible decrease in crow's feet depth over 8 weeks.
- 02 In vitro, concentrations of 0.5%-1.0% inhibited collagen-degrading matrix metalloproteinases (MMPs), contributing to a firmer skin texture.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Heat stable up to 40°C, it should be integrated into emulsions during the cooling phase. It demonstrates high stability in water-based serum and toner formulations.
Conflicts
- Strong oxidizing agents
- Highly acidic environments (pH < 4.0)
Safety
Safety Profile
While not formally reviewed by CIR, related Akebia plant parts are deemed safe. Oral toxicity studies suggest low toxicity, supporting its safety profile.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A highly effective anti-aging ingredient that comprehensively targets glycation, collagen degradation, and hydration for youthful, firm skin.
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References
Sources