Science
Mechanism of Action
It acts as an an anti-glycation and antioxidant agent, inhibiting AGE formation and suppressing ROS production by 88.3%. This promotes skin elasticity by stimulating fibrillin-1 and boosts urea production for enhanced moisturization.
Research
Clinical Evidence
Medium confidence0.5%
Key findings
- 01 Clinical evaluation (0.5-2%) over eight weeks showed decreased depth of crow's feet wrinkles.
- 02 In vitro, it suppressed ROS production by 88.3% and inhibited cellular senescence in human dermal fibroblasts.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Stable in water-based systems and often supplied in a water/glycerin base. Best added during the cooling phase of emulsions to protect sensitive antioxidant fractions.
Conflicts
- Strong oxidizing agents
- Highly acidic environments
Safety
Safety Profile
While not CIR-reviewed, clinical studies report no skin primary irritation in human subjects at typical usage levels of 0.5–2%.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Akebia Quinata Fruit Extract is a valuable anti-aging and moisturizing ingredient, demonstrated to reduce wrinkles and protect against oxidative stress with low irritation potential.
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References
Sources