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AGAVE AMERICANA LEAF EXTRACT.

Valuable CAS 85186-53-4 / SKIN CONDITIONING

Agave Americana Leaf Extract is a multi-functional ingredient valued for its significant hydrating, soothing, and skin-conditioning benefits. It also demonstrates anti-inflammatory, antioxidant, and wound-healing properties.

skin conditioning moisturizing soothing anti-inflammatory antioxidant wound healing

Science

It acts as a powerful humectant due to its high fructan content, attracting and retaining water in the skin's stratum corneum. Additionally, its steroidal saponins and flavonoids provide anti-inflammatory and antioxidant activity by reducing cytokines and scavenging free radicals.


Research

Medium confidence
Effective range 0.1–60%
Optimal

N/A

Key findings

  1. 01 Topical application of 10% hydroalcoholic extract significantly increased wound tensile strength and accelerated epithelialization in animal models.
  2. 02 1.0% W/V dry solid concentration proved safe and non-irritating in guinea pig cumulative irritation tests.
  3. 03 Formulations containing 0.1% to 60% of the extract were proposed for moisturizing, whitening, and inhibiting contact dermatitis.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 4.5 – 7
0 7 14

Stability

Stable in weak acids and alkalis, but susceptible to degradation at very high temperatures and strong oxidative conditions. Store away from extreme heat to preserve polyphenol bioactivity.

Conflicts

  • Strong oxidizing agents
  • Strong acids (pH < 3.0)
  • Strong bases (pH > 9.0)

Safety

CIR Status
Not reviewed
Sensitization risk Low

While CIR has not reviewed Agave Americana, processed cosmetic extracts are refined to remove irritants like calcium oxalate crystals and saponins found in raw sap, which can cause 'Agave Dermatitis'.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Agave Americana Leaf Extract is a valuable, well-tolerated ingredient offering significant hydration, soothing, and reparative benefits for various skin types.


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