Science
Mechanism of Action
Aescin, its primary active component, safeguards the extracellular matrix by inhibiting hyaluronidase and collagenase enzymes. It also tightens skin and reduces wrinkles by stimulating fibroblast contraction and improves microcirculation to decrease edema.
Research
Clinical Evidence
High confidence3%
Key findings
- 01 Topical application of 3.0% extract (standardized to aescin) reduced eye contour wrinkles by inducing fibroblast contraction over 9 weeks.
- 02 In vitro and ex vivo testing of 2.0% concentration demonstrated up to 68% reduction in intracellular oxidation and improved UV absorption properties.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Highly stable in aqueous systems at physiological pH, tolerates heating up to 85°C for short periods. Often stabilized with cyclodextrins.
Conflicts
- Strongly acidic environments (pH < 4.0)
- Cationic surfactants
- Strong oxidizing agents
Safety
Safety Profile
While CIR has not reviewed it, its close relative Aesculus hippocastanum is generally considered safe up to 3% and listed in EU CosIng without major restrictions.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This extract is a valuable multi-functional ingredient for targeted anti-aging, firming, and soothing applications across all skin types.
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References
Sources