Science
Mechanism of Action
This copolymer creates a continuous, thin, and flexible film on the skin surface. This film reduces transepidermal water loss (TEWL), thereby helping to maintain skin hydration and impart a smoother appearance.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 A 5% aqueous solution was found to be non-irritating in a human dermal irritation assay.
- 02 In vitro ocular irritation assays showed negative results at a 3% concentration.
- 03 A skin sensitization assay in guinea pigs using a 32% mixture demonstrated no signs of sensitization.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Stable at room temperature, but can release ammonia gas if heated above 84°C. Requires neutralization for optimal viscosity in aqueous solutions.
Conflicts
- Multivalent metal cations (e.g., Ca2+, Mg2+) can cause precipitation.
- Strongly acidic environments may destabilize the copolymer structure.
- Anionic surfactants at high concentrations may affect film clarity.
Safety
Safety Profile
The CIR Expert Panel concluded it is safe provided residual acrylamide monomer does not exceed 5 ppm. Its large molecular weight precludes dermal absorption.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This ingredient is a valuable film-former and viscosity enhancer, providing hydrating and smoothing benefits with a proven low risk of irritation or sensitization across all skin types.
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References
Sources