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Moumoujus

ACORUS CALAMUS CALLUS CULTURE EXTRACT.

Valuable CAS 84775-39-3 / ANTIOXIDANT, HAIR CONDITIONING, SKIN PROTECTING

A biotech-derived ingredient, this extract demonstrates potent regenerative properties. It actively promotes advanced wound healing and tissue repair, while delivering significant antioxidant and anti-inflammatory benefits.

Summary

antioxidant soothing antimicrobial skin conditioning

Science

Mechanism of Action

This extract acts by reducing inflammatory cytokines (IL-1β, IL-6, TNF-α) and inhibiting apoptosis. It concurrently promotes angiogenesis through VEGF and bFGF upregulation, neutralizes free radicals, and prevents collagen glycation for enhanced skin integrity.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In a rat model, a 20% concentration achieved 88.97% wound healing for radiation-induced skin injury by reducing inflammation and promoting angiogenesis.
  2. 02 Topical application significantly increased collagen, hexosamine, and uronic acid in granulation tissue, boosting tensile strength by 112% and reducing lipid peroxide levels.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH 4 – 6.8
0 7 14

Stability

Callus culture extracts are typically water-dispersible, with optimal stability observed in emulsions between pH 4-6 (toners) and 6.28-6.8 (lotions/gels).

Conflicts

  • High heat (can degrade volatile bioactives)
  • Strong oxidizing agents

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
0.78%
Sensitization risk Low

Traditional Acorus Calamus extracts are restricted to 0.13-0.78% in leave-on products due to potential β-asarone content. While this is a newer callus culture derivative, formal CIR review is pending.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

This ingredient offers significant regenerative, anti-inflammatory, and antioxidant benefits, making it a valuable addition for skin repair and anti-aging formulations.

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