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ACID RED 52.

Valuable CAS 3520-42-1 / HAIR DYEING

Acid Red 52, also known as CI 45100, is a synthetic xanthene dye primarily utilized as a cosmetic colorant. It imparts a vibrant fluorescent pinkish-red hue to formulations.

Summary

colorant hair dyeing

Science

Mechanism of Action

As a direct xanthene dye, Acid Red 52 adheres to the hair shaft surface or diffuses into the cuticle, providing color without chemical reaction. Its mechanism focuses on physical deposition rather than structural alteration.

Research

Clinical Evidence

High confidence
Effective range 0.6–1.5%
Optimal

N/A

Key findings

  1. 01 SCCNFP/SCCP concluded safe for use in semi-permanent hair dye formulations at this maximum concentration.
  2. 02 SCCP concluded safe for on-head application in oxidative hair dye formulations.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 1 – 13
0 7 14

Stability

Highly stable in water, ethanol, and under oxidative conditions, Acid Red 52 resists heat and light fading. It displays yellow fluorescence under UV light.

Conflicts

  • Cationic surfactants (may cause precipitation)
  • Strong reducing agents

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
1.5%
Sensitization risk Low

While not specifically reviewed by the CIR, the SCCS/SCCP has deemed it safe for hair dyes up to 0.6% (non-oxidative) and 1.5% (oxidative). It is considered non-sensitizing and non-irritating at typical use levels.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Acid Red 52 is a well-researched, stable, and versatile colorant, providing a vibrant pinkish-red hue for various cosmetic and hair care formulations at evaluated safe concentrations.

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