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ACID RED 51.

Avoid CAS 16423-68-0; 1342-25-2 / COLORANT, HAIR DYEING

Acid Red 51, also known as Erythrosine, is a xanthene dye primarily used as a cosmetic colorant, imparting a cherry-pink to red hue. While effective as a biological stain for non-viable cells and plaque, it offers no active skincare benefits.

colorant

Science

This tetraiodofluorescein dye functions by absorbing and reflecting light in the visible spectrum (λmax ~525-530nm) to create color. It also binds to proteins and cellular structures, which facilitates its use as a biological stain.


Research

Low confidence
Effective range 0.1–1%
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 6 – 7
0 7 14

Stability

Highly stable in neutral to alkaline conditions (pH 6-7), but sensitive to photolysis in aqueous solutions and can precipitate in acidic environments.

Conflicts

  • strong oxidizing agents
  • strong acids
  • some metallic ions

Safety

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Low

The FDA terminated Acid Red 51's provisional listing for cosmetics and externally applied drugs in 1990 due to concerns over thyroid tumors in high-dose animal studies. It remains restricted, though permitted in hair dyes up to 1% in the EU.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Avoid

Due to its non-functional role in skincare and past FDA termination for cosmetic use, this ingredient is not recommended for topical formulations.


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