Science
Mechanism of Action
This tetraiodofluorescein dye functions by absorbing and reflecting light in the visible spectrum (λmax ~525-530nm) to create color. It also binds to proteins and cellular structures, which facilitates its use as a biological stain.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Highly stable in neutral to alkaline conditions (pH 6-7), but sensitive to photolysis in aqueous solutions and can precipitate in acidic environments.
Conflicts
- strong oxidizing agents
- strong acids
- some metallic ions
Safety
Safety Profile
The FDA terminated Acid Red 51's provisional listing for cosmetics and externally applied drugs in 1990 due to concerns over thyroid tumors in high-dose animal studies. It remains restricted, though permitted in hair dyes up to 1% in the EU.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Due to its non-functional role in skincare and past FDA termination for cosmetic use, this ingredient is not recommended for topical formulations.
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