Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

ACHYROCLINE SATUREIOIDES FLOWER/LEAF/STEM EXTRACT.

Valuable CAS 92346-81-1 / SKIN CONDITIONING

This botanical extract promotes skin regeneration and wound healing by enhancing keratinocyte proliferation. Rich in flavonoids, it also provides antioxidant, antimicrobial, and soothing benefits for overall skin health.

antioxidant skin conditioning antimicrobial soothing

Science

Its primary action stems from flavonoids like quercetin and luteolin, which scavenge ROS, inhibit lipid oxidation, and stimulate collagen. It further offers antimicrobial protection against common skin bacteria.


Research

High confidence
Effective range 0.0000035–0.0000635%
Optimal

1%

Key findings

  1. 01 A 1.0% (w/v) nanoemulsion containing the dry extract demonstrated significant wound healing by increasing human keratinocyte migration and proliferation without cytotoxicity.
  2. 02 In vitro studies on human keratinocytes (HaCaT) showed the extract increased cell viability and renewal, suggesting potential as an anti-aging and regenerative agent at 3.5–63.5 μg/mL.

Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH 4.5 – 6
0 7 14

Stability

Exhibits good thermal and photo-stability as a spray-dried powder. In liquid formulations, nanoemulsions are recommended to stabilize poorly water-soluble flavonoids.

Conflicts

  • Unsuitable for feminine hygiene due to low efficacy against specific pathogens.
  • Potential instability in high alkaline environments (pH > 7.0) due to flavonoid degradation.

Safety

CIR Status
Not reviewed
Sensitization risk Low

Though not CIR reviewed, studies confirm it is hypoallergenic and non-cytotoxic to human keratinocytes. Animal studies show very low acute toxicity (LD50 > 5 g/kg).


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

This extract is a valuable multi-functional ingredient, offering significant regenerative, antioxidant, and soothing benefits for various skin concerns with high compatibility.


Related

Finding similar ingredients…


References