Science
Mechanism of Action
It downregulates proinflammatory cytokines like IL-6 and TNF-alpha, while stimulating fibroblast and keratinocyte proliferation via MAPK and STAT-2 pathways to promote tissue regeneration. Chamazulene and apigenin further contribute to its potent antioxidant and soothing effects.
Research
Clinical Evidence
High confidence1%
Key findings
- 01 At 1.0% concentration, Achillea Millefolium Oil significantly enhanced keratinocyte viability by 117.5% and Human Dermal Fibroblast viability by 114.8%, demonstrating strong potential for skin regeneration and wound healing.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The oil is highly sensitive to light and heat due to its chamazulene content, requiring storage in dark glass. It should be added to formulations during the cool-down phase at temperatures below 40°C.
Conflicts
- Strong oxidizing agents
- Strongly alkaline environments (pH > 7.0)
Safety
Safety Profile
While considered safe and non-irritating at typical cosmetic use levels (up to 0.5%), individuals with Compositae allergy may experience cross-reactivity. Constituents like thujone and camphor are usually below toxic thresholds in cosmetic applications.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Achillea Millefolium Oil is a valuable ingredient for its proven regenerative, anti-inflammatory, and antioxidant benefits, suitable for a wide range of skin types with low irritation risk.
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