Science
Mechanism of Action
It inhibits COX and PGE2 to reduce inflammation, while flavonoids and chamazulene provide antioxidant protection and soothe irritation. Tannins offer natural astringent effects, and it promotes wound healing via Akt phosphorylation and beta-catenin pathways.
Research
Clinical Evidence
Medium confidence0.5%
Key findings
- 01 At 0.04%, it was confirmed non-irritating and non-sensitizing in human repeat insult patch tests involving 53 subjects.
- 02 Incorporated into nanoemulsions, extract concentrations from 0.1% to 1.0% demonstrated potent antioxidant activity. A 0.5% concentration enhanced in vitro SPF from 14 to 22 when combined with chemical filters.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Best maintained in slightly acidic conditions, it is typically a brown-green liquid. High heat during processing can degrade volatile components like chamazulene.
Synergies
- Glycol-based vehicles (improves bioavailability)
- Chemical filters (enhanced photoprotection)
Conflicts
- Strong oxidizing agents
- High heat during processing
Safety
Safety Profile
The CIR Expert Panel concluded it is safe when formulated to be non-sensitizing, particularly addressing concerns with Compositae family plants.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This versatile botanical juice offers significant soothing, antioxidant, and astringent benefits, making it a valuable addition for diverse skin concerns.
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Similar Ingredients
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References
Sources