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ACETYLCEDRENE.

Optional CAS 32388-55-9 / PERFUMING

Acetylcedrene is a perfuming agent that imparts a woody, amber, and musk-like aroma to skincare formulations. It provides an aesthetic sensory experience without primary therapeutic benefits.

perfuming

Science

It functions strictly as an organoleptic agent, providing a scent profile. While it penetrates the skin at approximately 13.5% of the applied dose, it lacks documented anti-aging or anti-acne mechanisms.


Research

High confidence
Effective range 0.1–1.5%
Optimal

N/A

Key findings

  1. 01 An in vitro human skin absorption study demonstrated a dermal penetration rate of 13.52% of the applied dose (RIFM 2001a).
  2. 02 Established as a No Expected Sensitization Induction Level (NESIL) of 35000 µg/cm², supporting safe use in fragranced cosmetic products (RIFM/IFRA 2023).
  3. 03 Identified as typical concentrations in consumer products without adverse reporting (Food and Cosmetics Toxicology 1975).

Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Stable for 24+ months, as a ketone it is relatively stable compared to aldehydes. Store in cool, dry places away from heat and light to prevent oxidation.

Conflicts

  • Strong oxidizing agents
  • Strong bases

Safety

CIR Status
Not reviewed
Max tested
1.5%
Sensitization risk Low

Though not formally reviewed by CIR, IFRA heavily regulates it. It is considered non-genotoxic and non-clastogenic, with RIFM assessments supporting its safety in common use levels (0.1-1.5%).


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Optional

Acetylcedrene is a safe and well-regulated fragrance ingredient that provides a desirable scent profile without offering direct therapeutic skin benefits.


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