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ACETYLARGINYLTRYPTOPHYL DIPHENYLGLYCINE.

Valuable CAS - / SKIN CONDITIONING

This tetrapeptide is an active ingredient focused on improving skin elasticity and firmness. It targets signs of aging by supporting the skin's structural integrity.

Peptide Anti-Ageing Soothing Firming Agent Elastase Inhibitor

Science

The peptide primarily functions by inhibiting elastase, an enzyme that degrades elastin and collagen in mature skin, while stimulating type I collagen synthesis. This dual action restores skin integrity and improves elasticity.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 An 8-week in-vivo test applying 4% Relistase (peptide solution with glycerin) on mature women (average age 49) resulted in a 14% improvement in skin elasticity and a 15.6% increase in skin tightness.

Transparency

Not commonly dusted

No specific data regarding dusting practices for this ingredient was found in the provided research. It is a peptide, typically incorporated into formulations at specific concentrations.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Often supplied as a solution with glycerin, suggesting good water solubility. Specific optimal pH range for stability is not readily available.


Safety

CIR Status
Not reviewed
Sensitization risk Low

This ingredient has not been reviewed by CIR or SCCS. It is generally considered safe for topical use, with side effects being uncommon. EWG notes low concerns for various toxicities.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Acetylarginyltryptophyl Diphenylglycine is a valuable peptide for anti-aging and firming, showing promising in-vivo results for elasticity and tightness, with low irritancy and broad skin compatibility.


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