Science
Mechanism of Action
This 'omni-antioxidant' functions through four primary pathways: chemically scavenging reactive oxygen species and anions, physically quenching singlet oxygen and photoexcited states, selectively chelating transition metals, and modulating the matrisome to boost collagen and reduce inflammation.
Research
Clinical Evidence
High confidence1%
Key findings
- 01 Significant reduction over 8 weeks in average wrinkle severity (-25.7%), total wrinkle volume (-30.1%), pigment intensity (-25.6%), and redness intensity (-20.7%) compared to placebo.
- 02 Lotion with 1% AZ significantly reduced skin redness by 33-39% following low/high irradiance UV exposure.
- 03 Dose-dependent reduction of intracellular ROS formation in keratinocytes by 35-46%.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Highly photostable and heat stable up to 70°C, it also protects unstable ingredients like Tetrahexyldecyl Ascorbate (THDC) from degradation.
Synergies
- Tetrahexyldecyl Ascorbate (THDC) stabilization
Conflicts
- Sodium hydroxide
- Potassium hydroxide
- Aluminum hydroxide
- Strongly alkaline conditions (pH > 7.0)
- Iron or copper ions (may cause discoloration)
Safety
Safety Profile
Though not formally CIR-reviewed, it is REACH-registered and documented as safe for topical use in ECHA dossiers. Clinical studies show no significant itching, burning, stinging, or sensitization at 1% concentration.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A valuable multifunctional antioxidant and skin protectant, effective at 1% for combating aging signs, redness, and oxidative stress across all skin types.
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References
Sources